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. 2021 Jan 25;13(2):156. doi: 10.3390/pharmaceutics13020156

Table 3.

Advantages and disadvantages of printing technologies used in tablet printing applications.

Printing Technology Advantages Disadvantages
FDM High drug loading
Can print complex shapes
Easy to adjust drug release profiles
Preprinting processes can take time
Possible thermal degradation of APIs
DIW High drug loading
No risk of thermal degradation
Possible phase separation of drug formulations
Hard to uniformly distribute APIs within the paste
Drying of the tablet is required post printing
SLS High resolution
No need for preprinting processes
Possible degradation of APIs due to sintering
SLA High resolution Possible degradation of APIs due to laser projected onto the drug-loaded solution
Additional post-printing processes needed, such as photocuring of the final product
DLP High resolution Possible degradation of APIs due to laser projected onto the drug-loaded solution
Additional post-printing processes needed, such as photocuring of the final product
Inkjet Versatility of the technology, can be used with heat or light-based approach Cannot be used with high drug loading
APIs can be affected by high shear rates during printing
BJ Uniform final product Highly porous final products lead to low mechanical properties
Requires additional post-printing processes such as sintering