Table 3.
Printing Technology | Advantages | Disadvantages |
---|---|---|
FDM | High drug loading Can print complex shapes Easy to adjust drug release profiles |
Preprinting processes can take time Possible thermal degradation of APIs |
DIW | High drug loading No risk of thermal degradation |
Possible phase separation of drug formulations Hard to uniformly distribute APIs within the paste Drying of the tablet is required post printing |
SLS | High resolution No need for preprinting processes |
Possible degradation of APIs due to sintering |
SLA | High resolution | Possible degradation of APIs due to laser projected onto the drug-loaded solution Additional post-printing processes needed, such as photocuring of the final product |
DLP | High resolution | Possible degradation of APIs due to laser projected onto the drug-loaded solution Additional post-printing processes needed, such as photocuring of the final product |
Inkjet | Versatility of the technology, can be used with heat or light-based approach | Cannot be used with high drug loading APIs can be affected by high shear rates during printing |
BJ | Uniform final product | Highly porous final products lead to low mechanical properties Requires additional post-printing processes such as sintering |