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. 2021 Jan 29;11(2):101. doi: 10.3390/life11020101

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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TSO-treated patients display significant parasite-specific antibody responses in serum against T. suis. Kinetics of T. suis adult excretory/secretory antigen (TsAdES)-specific (a) serum IgG and (b) serum IgE levels in placebo and TSO-treated patients. (c) Levels of TsAdES-specific IgG, IgG1, IgG2, IgG3, IgG4, and IgE 12 months following treatment start. (d) Immunoblot analysis displaying the kinetics and diversity of TsAdES-specific serum IgG for TSO-treated patient 010 (left panel) and for patients 002 and 013 at month 12 of treatment (right panel). In (c) results were tested for normal distribution using the Shapiro–Wilk normality test, followed by unpaired t-test or Mann–Whitney U test. * p < 0.05, ** p < 0.01, *** p < 0.001, n.s., not significant.