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Midpoint rooted phylogenetic tree based on core genome single-nucleotide polymorphisms (SNPs) at initial collection (C1) and follow-up after 8–15 years (C2; mean follow-up: 11 years) in S. aureus isolated from CRS patients. Clonal complexes are presented. Based on 110,026 SNPs in the ~2.21 Mbp conserved core genome of the reference chromosome. Scale bar indicates substitutions per site. Nasal sample collected at C1 for patient number 39 was missing.
