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Flowchart of the analysis process. CpGs, 5′-C-phosphate-G-3′; GO, Gene Ontology; HC, healthy control; hyper-down, hyper-methylated and down-regulated; hypo-up, hypo-methylated and up-regulated; KEGG, Kyoto Encyclopedia of Genes and Genomes; MDD, major depressive disorder; ROC, receiver operating characteristic; TSS, transcriptional start site; UTR, untranslated region. N, number of MDD or HC.
