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. 2021 Jan 27;12(2):176. doi: 10.3390/genes12020176

Table 3.

Univariate and multivariate analysis of overall survival.

Relapse-Free Survival Overall Survival
Variable Univariate Analysis Multivariate Analysis Univariate Analysis Multivariate Analysis
p-Value HR (95% CI) p-Value p-Value HR (95% CI) p-Value
Sex (M) 0.786 0.777 0.777
Age 0.744 0.346 0.346
Pstage (III and IV) 0.038 * 10.859 (0.963–122.475) 0.317 0.317
histologic type (2) 0.733 0.862 0.862
histologic grade (2) 0.714 0.976 0.976
histologic grade (3) 0.749 0.975 0.975
histologic grade (4) 0.984 1.000 1.000
LVI (1) 0.075 0.392 0.392
Venous invasion (1) 0.034 * 2.013 (0.507–7.985) 0.443 0.443
PNI (1) 0.090 0.428
miR323a3p×1000 (>0.1326 §) 0.258 0.745 (0.142–3.906) 0.728 0.405 487,477.61 (0.000–∞) 0.974
miR3825p×1000 (>2.1516 §) 0.132 9.399 (0.499–177.143) 0.135 0.961 5.016 (0.517–48.628) 0.164
miR376a5p×1000 (>0.1454 §) 0.251 0.231 (0.010–5.319) 0.360 0.471 0.00 (0.000–2.31 × 10302) 0.969

*: Statistically significant with p < 0.05. §: Cut off value was obtained by ROC analysis.