Table 1.
Patient characteristics on patients on extracorporeal membrane oxygenation (ECMO) before implantation according to survival (veno-arterial ECMO cohort).
VA Total (n = 300) |
VA Survivors (n = 153) |
VA Non-Survivors (n = 147) |
p-Value | |
---|---|---|---|---|
Demographics, vital signs & laboratory chemistry | ||||
Age in years | 57 (46–65) | 56 (42–63) | 58 (47–65) | 0.05 |
Weight in kg | 77 (70–90) | 78 (68–89) | 77 (70–90) | 0.946 |
Female sex | 101 (33.7%) | 53 (34.6%) | 48 (32.7%) | 0.72 |
Heart rate/min | 101 (82–120) | 106 (87–125) | 96 (80–119) | 0.059 |
Mean arterial pressure in mmHg | 68 (57–80) | 70 (57–80) | 66 (56–80) | 0.345 |
Glasgow Coma Scale | 3 (3–13) | 9 (3–15) | 3 (3–3) | <0.001 |
Acute renal failure | 160 (53.3%) | 76 (49.7%) | 84 (57.1%) | 0.195 |
Creatinine in mg/dL | 1.50 (1.04–2.18) | 1.50 (1.10–2.32) | 1.50 (1.00–2.07) | 0.66 |
Temperature in °C | 36.5 (35.3–37.2) | 36.6 (35.5–37.4) | 36.4 (34.8–37.1) | 0.025 |
Leucocytes/nL | 11.7 (7.9–16.9) | 11.8 (8.1–18.4) | 10.8 (7.5–16.0) | 0.116 |
Platelets × 103/µL | 131.5 (83.0–196.8) | 125.0 (82.0–193.0) | 141.0 (83.0–205.0) | 0.695 |
Cardiopulmonary resuscitation pre ECMO | 113 (37.7%) | 39 (25.5%) | 74 (50.3%) | <0.001 |
Mechanical ventilation pre-ECMO for >7 days | 136 (45.3%) | 78 (51.0%) | 58 (39.5%) | 0.045 |
Mechanical ventilatory settings | ||||
Inspiratory pressure in cmH2O | 24 (20–32) | 25 (20–33) | 23 (20–32) | 0.20 |
Blood gas analysis | ||||
pH | 7.27 (6.70–7.69) | 7.30 (6.80–7.69) | 7.23 (6.70 –7.57) | <0.001 |
PaO2 in mmHg | 77 (63–108) | 76 (64–100) | 80 (62–112) | 0.30 |
PaO2/FiO2 in mmHg | 105 (67–193) | 100 (67–190) | 113 (67–202) | 0.34 |
Bicarbonate in mmoL/L | 19 (14.2–22.1) | 20.4 (16.0–23.2) | 18 (13.0–21.1) | <0.001 |
Lactate in mmoL/L | 5.3 (2.3–10.5) | 4.4 (1.9–8.4) | 7.1 (3.0–11.5) | 0.001 |
Data are expressed as n (%), or median (interquartile range); significant p values (p < 0.05) marked in bold.