Changes in food intake and body weight with the astaxanthin (AX) diet: (a) food intake; (b) body weight. Mice were fed an AX or normal diet for 6 weeks. They were subjected to tail suspension at 4 weeks, which continued for 2 weeks (C-ND, n = 6; S-ND, n = 6; C-AX, n = 6; S-AX, n = 6). Data are presented as mean ± S.D. (n = 6). Statistical analysis was performed by the two-way ANOVA and Tukey test. * p < 0.05, compared with ND. C-ND, control mice fed the normal diet; S-ND, tail-suspension mice fed the normal diet; C-AX, control mice fed the AX diet; and S-AX, tail-suspension mice fed the AX diet. Arrow means the time of tail suspension.