Table 1.

Viruses recognized by toll like receptors or TLRs.

PRRs/Receptor	Localization	Adapter	Viruses PAMPS	Viruses	Reference
TLR2	Cell membrane	MyD88	Envelope glycoprotein, core protein	Cytomegalovirus	[14]
				Hepatitis C virus	[13]
				Hepatitis B virus	[15]
				Herpes simplex virus	[16]
				Measles virus	[71]
				Varicella-zoster virus	[72]
				Epstein-Barr virus	[73]
				Vaccinia virus	[74]
				Junin virus	[18]
TLR3	Endosome	TRIF	dsRNA, RNA, siRNAs, self RNA, polyI:C	Respiratory syncytial virus	[33]
				Rhinovirus	[35]
				Reovirus	[31]
				Herpes simplex virus-2	[36]
				Influenza A virus	[40]
				Enterovirus A71	[41]
				Friend retrovirus	[42]
				West Nile virus	[45]
				Murine coronavirus	[44]
				Human immunodeficiency virus	[39]
				Epstein-Barr virus	[32]
				Hepatitis C virus	[43]
TLR4	Cell membrane	MyD88 and TRIF	Glycoprotein, envelop protein, fusion protein,	Vesicular stomatitis virus	[19]
				Ebola virus	[20]
				Mouse mammary tumor virus	[21]
				Moloney murine leukemia virus	[21]
				Coxsackie B virus	[75]
				Respiratory syncytial virus	[76]
				Human immunodeficiency virus	[22]
TLR7/8	Endosome	MyD88	ssRNA	Vesicular stomatitis virus	[52]
				Human immunodeficiency virus	[51]
				Coxsackie B virus	[49]
				Hepatitis C virus	[53]
				Sendai virus	[50]
				Influenza virus	[52]
				Rabies virus	[54]
				Friend murine leukemia virus	[55]
TLR9	Endosome	MyD88	Viral DNA	Herpes simplex virus 1	[64]
				Herpes simplex virus 2	[63]
				Varicella-zoster virus	[62]
				Cytomegalovirus	[59]
				Epstein-Barr virus	[61]
				Human immunodeficiency virus	[65]
				Hepatitis B virus	[66]
				Enterovirus 71	[67]
TLR10	Cell membrane	Unknown	Envelope protein, RNA	Influenza A virus	[68]
				Human immunodeficiency virus	[77]