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. 2021 Jan 28;10(2):124. doi: 10.3390/antibiotics10020124

Table 2.

List of endolysins in human clinical trials.

Endolysin Study Phase Clinical Trials Identifier Status
CF-301 Safety, Efficacy, and Pharmacokinetics of CF-301 vs. Placebo in Addition to Antibacterial Therapy for Treatment of S. aureus Bacteremia III NCT04160468 Ongoing trial
N-Rephasin® SAL200
(Intron Biotechnology, Inc., South Korea)
To evaluate safety and to explore the efficacy of a single intravenous dose of N-Rephasin® SAL200 (3 mg/kg) IIa NCT03089697 Ongoing trial
P-128 Safety & Efficacy of an Antibacterial Protein Molecule Applied Topically to the Nostrils of Volunteers and Patients II NCT01746654 Completed