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Polymorphisms affecting transcription factor (TF) binding sites in P.1 Brazilian severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant. (A) Mutation 26150 T/C causes formation of binding site for SPEDEF TF in P.1 sequence. (B, C) Mutation 6320 A/G leads to enrichment for binding sites of GRHL1 and TFCP2 TF.
