Table 3.
TF binding sites present exclusively in genome of SARS-CoV-2 isolated from humans and near starting site of each of virus gene or ORF
| TF name | TF ID | Start position | End position | Core match score | Matrix match score | Sequence |
|---|---|---|---|---|---|---|
| THRB (var. 2) | MA1575.1 | 5940 | 5958 | 0.964 | 0.858 | TTGACCCTAAGTTGGACAA |
| GLIS2 | MA0736.1 | 21633 | 21646 | 1 | 0.85 | TACCCCCTGCATAC |
| TFAP2A | MA0003.4 | 22207 | 22220 | 1 | 0.962 | TCTCCCTCAGGGTT |
| PAX6 | MA0069.1 | 17674 | 17687 | 1 | 0.878 | ATCACGCATGATGT |
| MZF1 | MA0056.2 | 29830 | 29842 | 1 | 0.952 | GCTATCCCCATGT |
| KLF4 | MA0039.4 | 11749 | 11760 | 1 | 0.885 | ACTCCCACCCAA |
| SP9 | MA1564.1 | 6188 | 6199 | 0.901 | 0.871 | TACACACCCTCT |
| SP9 | MA1564.1 | 11746 | 11757 | 0.899 | 0.857 | ACTACTCCCACC |
| Nr1h3::Rxra | MA0494.1 | 241 | 259 | 0.962 | 0.877 | TGTCCGGGTGTGACCGAAA |
| Nr1h3::Rxra | MA0494.1 | 20175 | 20193 | 0.962 | 0.904 | TGTCCAACAATTACCTGAA |
| E2F1 | MA0024.3 | 671 | 682 | 1 | 0.912 | TACGGCGCCGAT |
| EGR1 | MA0162.4 | 11747 | 11760 | 1 | 0.901 | CTACTCCCACCCAA |
| KLF11 | MA1512.1 | 6188 | 6198 | 0.933 | 0.912 | TACACACCCTC |
| TBXT | MA0009.2 | 2506 | 2521 | 0.946 | 0.883 | TCCCACAGAAGTGTTA |
| E2F6 | MA0471.2 | 23604 | 23616 | 1 | 0.883 | CTCGGCGGGCACG |
| E2F4 | MA0470.2 | 670 | 683 | 1 | 0.873 | TTACGGCGCCGATC |
| KLF16 | MA0741.1 | 6188 | 6198 | 0.908 | 0.9 | TACACACCCTC |
| Ebf2 | MA1604.1 | 6662 | 6674 | 0.913 | 0.908 | GTCCCTTGGGATA |
| ZBTB14 | MA1650.1 | 6358 | 6369 | 1 | 0.855 | GGACGCGCAGGG |
| EGR4 | MA0733.1 | 11747 | 11762 | 0.893 | 0.882 | CTACTCCCACCCAAGA |
| SP8 | MA0747.1 | 6188 | 6199 | 0.96 | 0.892 | TACACACCCTCT |
| SP8 | MA0747.1 | 11746 | 11757 | 0.964 | 0.876 | ACTACTCCCACC |
| KLF5 | MA0599.1 | 11750 | 11759 | 0.999 | 0.888 | CTCCCACCCA |
| EBF3 | MA1637.1 | 6662 | 6674 | 0.912 | 0.918 | GTCCCTTGGGATA |
| KLF9 | MA1107.2 | 6186 | 6201 | 1 | 0.886 | ACTACACACCCTCTTT |
We considered a range of ±1000 bases from starting sites. Abbreviations: ORF, open reading frame; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; TF, transcription factor.