Table 2.
Outcomes of the study.
| Outcomes | Neuropsychological Assessment |
|---|---|
| Primary outcomes | |
| MMSE | Global cognitive function |
| Digit Span | Attention and working memory |
| RAVLT (immediate and delayed recall) | Verbal immediate memory |
| VR (immediate and delayed recall) | Visuo–spatial function |
| Digit symbol substitution | Psychomotor speed |
| POMS | Tension, depression, anger, fatigue, esteem-related effect, vigor, and confusion |
| Secondary outcomes | |
| Biomarkers | BDNF, MDA, iNOS, COX-2, SOD, GSH |
| Biochemical profiles | Fasting blood sugar, lipid profile, liver function test, renal function test |
Abbreviation: BDNF: Brain derived neurotrophic factor; COX-2: Cyclooxygenase-2; GSH: Glutathione; iNOS: Inducible nitric oxide synthase; MDA: Malondialdehyde; MMSE: Mini-mental State Examination; POMS: Profile of Mood State; RAVLT: Rey Auditory Verbal Learning Test; SOD: Superoxide dismutase; VR: Visual reproduction.