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. 2021 Jan 29;13(2):434. doi: 10.3390/nu13020434

Table 5.

Intervention effect of biomarkers from baseline to 12th week.

CC Supplement (n = 23) Placebo (n = 24) Treatment × Time Effect
p Partial Eta Squared Power
Brain derived neurotrophic factor (BDNF) (pg/mL)
Baseline 180.80 ± 86.42 180.09 ± 95.78 0.884 0.001 0.052
12th week 194.74 ± 137.49 171.22 ± 113.87
Inducible nitric oxide synthase (iNOS) (pg/mL)
Baseline 220.38 ± 66.56 218.99 ± 74.66 0.994 0.000 0.050
12th week 216.34 ± 81.39 219.64 ± 80.67
Cyclooxygenase-2 (COX-2) (ng/mL)
Baseline 0.86 ± 0.42 1.08 ± 0.59 0.867 0.001 0.053
12th week 0.78 ± 0.43 1.15 ± 0.70
Superoxide dismutase (SOD) (pg/mL)
Baseline 49.13 ± 3.81 49.46 ± 2.64 0.577 0.008 0.085
12th week 51.63 ± 2.04 51.22 ± 3.50
Malondialdehyde (MDA) (ng/mL)
Baseline 350.14 ±161.08 358.21 ± 172.59 0.047 * 0.097 0.516
12th week 313.32 ± 153.35 398.94 ± 181.85
Glutathione (GSH) (mM)
Baseline 0.46 ± 0.09 0.48 ± 0.05 0.111 0.064 0.356
12th week 0.50 ± 0.06 0.48 ± 0.07

* Significance at p < 0.05. Controlled for age, physical activity, BMI, energy intake, vitamin A and C.