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. 2021 Feb 27;16:20. doi: 10.1186/s13011-021-00354-1

Table 3.

Linear mixed model of SCL-10 adjusted for clinical and sociodemographic factors

Fixed effects
Baseline Change per year
n = 707 Estimate (95% CI) Slope (95% CI)
Factor impact* on SCL-10 sum score at baseline and changes per year from baseline
 SCL-10 sum score 18.1 (15.9 to 20.2) 0.6 (−1.6 to 2.9)
 Female 1.8 (0.7 to 3.0) 0.4 (−0.9 to 1.8)
 Age per 10 years 0.0 (−0.1 to 0.0) 0.0 (0.0 to 0.1)
Clinical factors
 Injecting substance use
 Injecting at least once last 12 months 0.6 (−0.7 to 1.8) −0.3 (−1.6 to 1.0)
Frequent use of substances
 Alcohol 0.7 (−0.6 to 1.9) 0.1 (−1.2 to 1.4)
 Cannabis 1.3 (0.2 to 2.5) 0.3 (−0.9 to 1.4)
 Stimulants (amphetamines/ cocaine) −2.7 (−4.1 to − 1.4) − 0.2 (−1.6 to 1.3)
 Opioids (other than opioid dispensed on OAT) 2.7 (1.1 to 4.2) −2.6 (− 4.7 to − 0.4)
 Benzodiazepines 3.6 (2.4 to 4.8) − 0.4 (− 1.7 to 0.8)
Sociodemographic factors
 Level of education −0.1 (− 0.7 to 0.6) −0.6 (− 1.3 to 0.1)
 Unstable living conditions 1.7 (0.0 to 3.3) 1.1 (−1.0 to 3.3)
 Worrying debt situation 2.2 (1.1 to 3.3) 0.4 (−0.7 to 1.6)

SCL-10 = Symptoms checklist 10; ten items scale for measuring mental health status/psychological distress, CI = confidence interval

*Age per 10 years (centered according to mean age 43 years), level of education was coded 0–4 with 4 as the highest educational level, living conditions; unstable situation homeless or non-permanent residence, worrying debt situation: including any legal or illegal fees and debt, injecting substance use: during last 12 months