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. 2021 Jan 30;13(2):183. doi: 10.3390/pharmaceutics13020183

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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(A) SEM images of cross section of PCL-PLA20VE Bi-layer; k(i) PCL20VE; k(ii) PLA20VE. (B) Evaluation of angiogenic potential of the PCL/PLA asymmetric membranes with and without 20% of VE. The appearance and position of implanted membranes on CAM, at day 14 of fertilization, indicated by the circles. Blue arrows, on retrieved membranes, depict blood vessels infiltrated inside the explanted membrane. (C) Quantification of CAM assay by counting blood vessels around and inside the membranes, from the images taken at day 14, just before retrieving the membranes and sacrificing the eggs. The results are mean ± S.D. (*** p < 0.0001) of 4 viable chicks surviving from original group of 7 fertilized eggs per group. Reprinted with permission from [57], Elsevier, 2019.