Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Pro-inflammatory cytokine production after nicorandil treatment. No significant reduction of IL8 (A) and IL6 (B) protein levels were observable in nicorandil (500 μM) treated endothelial cells 8 h after stimulation with IL-1β. Furthermore, there was no change in MCP-1 mRNA levels 2 h after stimulation with IL-1β, as determined by real-time PCR (C). All values given represent means ± standard deviations; the statistical significance of p ≤ 0.05 was considered significant.
