. 2021 Jan 25;9(2):245. doi: 10.3390/microorganisms9020245

Table 3.

The specificity of each automated analyzer according to the negative control subgroups (n = 127).

Subgroup with IgG/IgM Antibodies Against:	No. of Samples	VIDAS^®3	CL-900i^®	LIAISON^®XL
Subgroup with IgG/IgM Antibodies Against:	No. of Samples	% (95% CI)	% (95% CI)	% (95% CI)
Other human CoVs (SARS-CoV, MERS-CoV, HCoV-229E, NL63, OC43, and HKU1)	18	18/18; 100 (82.4–100)	12/18; 66.7 (43.8–83.7)	18/18; 100 (82.4–100)
Non-CoV respiratory viruses (Influenza A and RSV)	38	37/38; 97.4 (86.5–99.5)	38/38; 100 (90.8–100)	38/38; 100 (90.8–100)
Non-respiratory viruses (HEV, HGV, HCV, HBV, DENV, WNV, CHIKV, B19, HSV-1, HSV-2, EBV, HHV-6, and HHV-8)	65	65/65; 100 (94.4–100)	65/65; 100 (94.4–100)	65/65; 100 (94.4–100)
Antinuclear antibodies (ANAs)	6	5/6; 83.3 (43.7–97.0)	6/6; 100 (61.0–100)	6/6; 100 (61.0–100)
Overall specificity	127	125/127; 98.4 (94.5–99.6)	121/127; 95.3 (90.1–97.8)	127/127; 100 (97.1–100)