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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
This depicts the various strategies adopted in the engineering of oncolytic viruses to grant selective tropism for malignant cells. The image was adapted from Groeneveldt et al., Trends Immunol 2020.