WHO	World Health Organization
HGG	high-grade glioma
CNS	central nervous system
BBB	blood–brain barrier
OV	oncolytic virus
Treg	regulatory T cell
MDSC	myeloid-derived suppressor cell
NK	natural killer
PAMP	pathogen-associated molecular pattern
PRR	pattern recognition receptor
DAMP	damage-associated molecular patterns
GM-CSF	granulocyte macrophage colony-stimulating factor
CTLA-4	cytotoxic T-lymphocyte associated protein 4
PD-1	programmed cell death protein-1
HSV	herpes simplex virus
FDA	Food and Drug Administration (of the United States)
CPA	cyclophosphamide
TMZ	temozolomide
CD	cytosine deaminase
5-FU	5-fluorouracil
CEA	carcinoembryogenic antigen
ECM	extracellular matrix