Figure 1.

Growth of a purine-deficient mutant of P. aeruginosa can be rescued in the presence of S. aureus. (A) Purine complementation in purine-deficient mutant (purC::tn) of P. aeruginosa by an expected/a probable purine-producing strain of S. aureus (JE2) in co-culture. (B) Relative bacterial abundance of JE2 in co-culture with PA14 or purC::tn mutant strain of P. aeruginosa compared to JE2 monoculture. Error bars represent SEM of data derived from three biological replicates on different days, and experiments were performed in technical triplicates each day. Here, ‘’**’’ designates p < 0.005, ‘’****’’ designates p < 0.0001 as depicted by two-tailed unpaired Student’s t-test, and ns denotes not significant (p > 0.05).