Table 2.
Introduction of protein substitutes.
| Laboratory produced preparation | |
| 1952 |
Hydrolysed casein, powdered preparation, nutritionally incomplete, low phenylalanine Addition of tyrosine, tryptophan and methionine, carbohydrate, fat, vitamins and minerals |
| Commercial produced preparations | |
| 1954 |
Hydrolysed casein, powdered preparation, nutritionally incomplete, low phenylalanine Trufood (infant product), Allen and Handbury/Mead Johnson (older children) |
| 1960 |
L amino acid, powdered preparation, nutritionally incomplete phenylalanine free Powell and Scholfield powdered preparation taken as a drink |
| 1980 |
L amino acid, powdered preparation with added carbohydrate and fat nutritionally complete, phenylalanine free Powdered flavoured preparation taken as a drink |
| 1988 |
L amino acid, powdered preparation with added carbohydrate and fat nutritionally complete, phenylalanine free Powdered preparation taken as a drink for >8 years and adults |
| 1988 |
L amino acid, powdered preparation, with added carbohydrate and fat, nutritionally complete designed for infants, phenylalanine free Powdered preparation used for infants 0–12 months |
| 2001 |
L amino acid, powdered preparation with added carbohydrate and essential fatty acids, nutritionally complete, phenylalanine free Powdered flavoured preparation taken as a drink |
| 2001 |
L amino acid powdered preparation, spoonable paste added carbohydrate, fat free, nutritionally complete, phenylalanine free Powdered flavoured preparation taken as a spoonable paste |
| 2002 |
L amino acid tablets, nutritionally incomplete, phenylalanine free Amino acid tablets |
| 2003 |
L amino acid powdered preparation, low carbohydrate, no fat, nutritionally complete, phenylalanine free Powdered flavoured preparation taken as low volume drink or spoonable paste for children >8 years |
| 2006 |
L amino acid ready to drink preparation, low carbohydrate no fat, nutritionally complete, phenylalanine free Ready to drink flavoured liquid |
| 2008 |
Casein macropeptide with L amino acids, essential fatty acids, nutritionally complete, low phenylalanine Powdered preparation made into a low volume drink |
| 2008 |
Casein macropeptide with L amino acid nutritionally complete with essential fatty acids, low phenylalanine. Powdered preparation make into a low volume drink |
| 2018 |
Slow release L amino acid preparation, carbohydrate and fat free, nutritionally complete, phenylalanine free Micro tablets, made from L amino acids coated with ethyl cellulose and alginate which slowly release the L amino acids |