Table 1.
Immunohistochemical expression of PTEN, phospho-AKT (p-AKT), and Rictor in the canine and feline mammary tumors examined.
| Tumors | PTEN | p-AKT | Rictor | |||
|---|---|---|---|---|---|---|
| Positive | % | Positive | % | Positive | % | |
| DOG | ||||||
| Adenomas | 10/10 a | 100 | 0 | 0 | 1 | 10 |
| Carcinomas | 25/40 | 62.5 | 15/40 b | 37.5 | 24/40 c | 60 |
| CAT | ||||||
| Carcinomas | 7/30 | 23.3 | 24/30 | 80 | 20/30 | 66.7 |
Fisher test analysis: a PTEN expression was significantly higher (p = 0.021) in canine mammary adenomas than in canine carcinomas. b p-AKT expression was significantly higher (p = 0.021) in canine mammary carcinomas than in canine adenomas. c Rictor expression was significantly higher (p = 0.005) in canine mammary carcinomas than in canine adenomas.