Figure 5.

In vitro activities of 5FC alone (0.1 µg/mL) and in combination with FLC 25 µg/mL; (a), ITC 4 µg/mL; (b), VRC 1 µg/mL; (c), and POS 4 µg/mL; (d) against C. glabrata IFM60089 as determined by the time-killing assay. The detection limit was 20 CFU/mL. Dashed lines represent a >99.9% growth reduction compared with the initial inoculum size for determination of fungicidal activity. All 5FC combinations with azoles showed indifferent interactions. Each data point represents the means ± standard deviation of results from two independent experiments.