Table 2.

Comparative Genomics among LA ST398 MRSA S0385, human animal-independent ST398 MSSA NM01 and M1/M2 ST398 MSSA.

Strain	mec Gene	MLST	spa-Type	Capsular Type	agr-Group	Plasmid rep Gene	MGEs	Prophage	Resistome	Adhesin Genes
										clfA	clfB	fnbA	fnbB	CoA	sdrE	sdrC	sdrD	cna
LA-MRSA SA0385	mecA	ST398	t011	Cap5	I	repUS43 CDS12738 (DOp1)	ISSau5 (2 copies) ISSau1 (4 copies) Tn6009	φ7401PVL PT1028 23MRA	mecA blaZ tetM	truncated	truncated	WT	truncated	Δ81bp	absent	Δ174bp	3SNPs	WT
Human-animal independent MSSA NM01	-	ST398	t571	Cap5	I	rep13 (pSSP1)	CT Cn_30859-ISSau1 (4 copies)	φNM3 R8A2B	blaZ ermT	WT	WT	WT	WT	WT	WT	WT	Δ54bp	ΔBdomain
M1/M2 MSSA	-	ST398	t1451	Cap5	I	rep13 (pC194)	ISSau8 (1 copy)	StauST398-4	blaZ ermT	WT	WT	WT	WT	WT	WT	WT	3SNPs	WT

Legend: IS = Insertion Sequence; CT = Composite Transposon; MGEs = Mobile Genetic Elements.