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. 2021 Feb 2;9(2):306. doi: 10.3390/microorganisms9020306

Figure 5.

Figure 5

Adherence of Clostridioides difficile to Caco-2 cells is reduced by CD0873 antibodies. Adherence of C. difficile to Caco-2 monolayers after the bacterial cells were pre-incubated with (A) intestinal fluid diluted 1:2 and (B) sera diluted 1:5 from CD0873 orally immunised hamsters or from naïve hamsters. Cell-binding was measured by enumerating CFU from washed Caco-2 cells. The values are mean numbers of adherent bacteria per 100 Caco-2 cells. The assay was performed in triplicate. Error bars represent standard error of the mean (SEM). A non-parametric Mann–Whitney U test was performed to compare groups. Statistical difference p-value; (*) p < 0.05 and (***) p < 0.001.