Table 2.
22 ferroptosis-related potential prognostic genes generated from the training cohort.
| Gene Symbol | Description | Category | Genomic Location | Kaplan–Meier Analysis (p-Value) | Univariate Cox Regression Analysis | |||
|---|---|---|---|---|---|---|---|---|
| HR | HR_95L | HR_95H | p-Value | |||||
| VDAC1 | Voltage Dependent Anion Channel 1 | Protein Coding | chr5 | 7.12 × 10−6 | 5.291343594 | 1.781142996 | 15.71929771 | 2.71 × 10−3 |
| STEAP3 | STEAP3 Metalloreductase | Protein Coding | chr2 | 3.19 × 10−3 | 4.206162616 | 2.092921898 | 8.453160136 | 5.49 × 10−5 |
| SLC39A8 | Solute Carrier Family 39 Member 8 | Protein Coding | chr4 | 3.77 × 10−2 | 3.869852511 | 1.326333156 | 11.29109861 | 1.33 × 10−2 |
| SLC11A2 | Solute Carrier Family 11 Member 2 | Protein Coding | chr12 | 4.76 × 10−3 | 3.094601274 | 1.570769273 | 6.096730571 | 1.09 × 10−3 |
| PEBP1 | Phosphatidylethanolamine Binding Protein 1 | Protein Coding | chr12 | 4.86 × 10−2 | 0.234529606 | 0.075635069 | 0.727230595 | 1.20 × 10−2 |
| MAPK1 | Mitogen−Activated Protein Kinase 1 | Protein Coding | chr22 | 9.03 × 10−3 | 2.895607401 | 1.163501743 | 7.206299663 | 2.23 × 10−2 |
| MAP1LC3C | Microtubule Associated Protein 1 Light Chain 3 Gamma | Protein Coding | chr1 | 1.31 × 10−2 | 0.459748503 | 0.271733125 | 0.777853955 | 3.78 × 10−3 |
| LINC00472 | Long Intergenic Non-Protein Coding RNA 472 | RNA Gene | chr6 | 6.36 × 10−3 | 0.043258919 | 0.003322917 | 0.563160037 | 1.65 × 10−2 |
| ITGA6 | Integrin Subunit Alpha 6 | Protein Coding | chr2 | 1.13 × 10−3 | 4.613594536 | 2.148024539 | 9.909223176 | 8.85 × 10−5 |
| HSPA5 | Heat Shock Protein Family A (Hsp70) Member 5 | Protein Coding | chr9 | 8.91 × 10−3 | 2.25326069 | 1.228917946 | 4.131426149 | 8.63 × 10−3 |
| HMOX1 | Heme Oxygenase 1 | Protein Coding | chr22 | 2.19 × 10−3 | 2.334473768 | 1.59857086 | 3.409149952 | 1.14 × 10−5 |
| GSS | Glutathione Synthetase | Protein Coding | chr20 | 3.31 × 10−3 | 3.851728269 | 1.85357871 | 8.003874117 | 3.02 × 10−4 |
| FTH1 | Ferritin Heavy Chain 1 | Protein Coding | chr11 | 4.64 × 10− 3 | 4.040699109 | 1.10619952 | 14.75976891 | 3.46 × 10−2 |
| CD44 | CD44 Molecule (Indian Blood Group) | Protein Coding | chr11 | 6.66 × 10− 3 | 0.304760194 | 0.142947413 | 0.649740862 | 2.10 × 10−3 |
| CASP8 | Caspase 8 | Protein Coding | chr2 | 3.91 × 10−2 | 2.604965341 | 1.209052632 | 5.612530215 | 1.45 × 10−2 |
| BAP1 | BRCA1 Associated Protein 1 | Protein Coding | chr3 | 1.40 × 10−6 | 0.561778701 | 0.412394493 | 0.765275275 | 2.56 × 10−4 |
| AURKA | Aurora Kinase A | Protein Coding | chr20 | 2.54 × 10−2 | 3.390492663 | 1.565174215 | 7.344511806 | 1.96 × 10−3 |
| ANO6 | Anoctamin 6 | Protein Coding | chr12 | 2.56 × 10−2 | 2.263254914 | 1.292723147 | 3.962428319 | 4.26 × 10−3 |
| ALOX12 | Arachidonate 12-Lipoxygenase, 12S Type | Protein Coding | chr17 | 1.48 × 10−3 | 0.022909689 | 0.002539428 | 0.20668188 | 7.66 × 10−4 |
| AIFM2/FSP1 | Apoptosis Inducing Factor Mitochondria Associated 2 | Protein Coding | chr10 | 6.03 × 10−6 | 6.104896507 | 2.780109603 | 13.40586045 | 6.55 × 10−6 |
| ACSL6 | Acyl-CoA Synthetase Long Chain Family Member 6 | Protein Coding | chr5 | 4.56 × 10−4 | 2.283441779 | 1.099533069 | 4.742109633 | 2.68 × 10−2 |
| ACSL1 | Acyl-CoA Synthetase Long Chain Family Member 1 | Protein Coding | chr4 | 6.64 × 10−3 | 1.873686292 | 1.236619189 | 2.838950221 | 3.06 × 10−3 |