Table 1.

Analysis of Response Data.

Tumor Size
Tumor size at start of treatment: Tumor size prior to surgery:	113 mm (range, 65–330 mm) (measured by CT/MRI) 69 mm (range, 25–228 mm) (measured by CT/MRI)
Tumor size at resection specimen:	62 mm (range, 22–200 mm) (measured by pathology)
Pathology Review of the Resection Specimen
Complete necrosis (no viable tumor cells)	n = 12 (24%)
Near total (>95% necrosis)	n = 10 (20%)
Subtotal (>90% necrosis)	n = 7 (14%)
Partial remission (>50% necrosis)	n = 14 (28%)
Stable disease (<50% necrosis)	n = 7 (14%)
Correlation of Response to Therapy (Pearson, Two-Sided; Spearman)
Δtumor diameter pre vs. post		p = 0.078	p = 0.089
RECIST 1.1		p = 0.2	p = 0.21
Mutational type exon 11		p = 0.04	p = 0.037
	point mutation
	del involving codons 557_558
	others