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. 2021 Feb 3;14(2):115. doi: 10.3390/ph14020115

Figure 1.

Figure 1

Workflow for the simulation study to assess the impact of two non-adherent scenarios compared to the full adherent scenario (0 missed doses/week, top) on endoxifen target attainment for five different dosing strategies comprising genotype-predicted normal metabolisers (gNM), intermediate metabolisers (gIM) and poor metabolisers (gPM).