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. 2021 Feb 2;9(2):117. doi: 10.3390/vaccines9020117

Table 2.

Reported error or related problems regarding reconstituted vaccines by profession.

Errors Physician (n = 250) Nurse (n = 450) p-Value
Experienced an error related to reconstituted vaccines, n (%)
Yes 191 (76.4) 187 (41.5) <0.0001
No 37 (14.8) 170 (37.8)
Uncertain 22 (8.8) 93 (20.7)
Type of error, n (%) (multiple selections)
Inadequate shaking of vaccine 129 (51.6) 86 (19.1) -
Incomplete aspiration of the reconstitution vial 130 (52.0) 66 (14.7)
Spillage or leakage during reconstitution 106 (42.4) 66 (14.7)
Needle twisted when inserted in vial stopper 74 (29.6) 53 (11.8)
Same needle used for reconstitution and injection 58 (23.2) 45 (10.0)
Forgetting to reconstitute the vaccine 48 (19.2) 34 (7.6)
Loss of equipment for reconstitution 40 (16.0) 28 (6.2)
Reconstitution with incorrect diluent 39 (15.6) 22 (4.9)
Frequency of an error occurring, n (%)
Never 22 (8.8) 219 (48.7) <0.0001
<one in 1000 vaccinations 52 (20.8) 78 (17.3)
One in 1000 vaccinations 27 (10.8) 41 (9.1)
One in 500 vaccinations 48 (19.2) 35 (7.8)
One in 100 vaccinations 72 (28.8) 43 (9.6)
>one in 100 vaccinations 29 (11.6) 34 (7.6)
Cause of error, n (%) (multiple selections)
Being less careful because of overall workload 132 (57.5) 59 (25.5) -
Having insufficient time to prepare the vaccine 77 (33.8) 98 (42.4)
Paying less attention to complete dissolution 77 (33.8) 63 (27.3)
Having complex process in preparing of the vaccine 62 (27.2) 103 (44.6)
Frequency of preparation of new vaccine when an error occurs, n * (%) 228 (100.0) 231 (100.0)
Never 67 (29.4) 57 (24.7) 0.1193
25% of the time 37 (16.2) 28 (12.1)
50% of the time 14 (6.1) 10 (4.3)
75% of the time 6 (2.6) 14 (6.1)
Always 104 (45.6) 122 (52.8)

n *: number of respondents who experienced an error.