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. 2021 Feb 3;13(2):496. doi: 10.3390/nu13020496

Figure 1.

Figure 1

The possible effects of high total fat, saturated fatty acids (SFAs) and trans fatty acids (TFAs) intake on prostate cancer progression. IGFBP: insulin growth factor binding protein (inhibited activity/protein level reduction). NF-κB: nuclear factor kappa B (increased expression). STAT-3: signal transducer and activator of transcription 3 (increased expression). T, DHT, E2: testosterone, dihydrotestosterone, 17β-estradiol (increased secretion). ROS: reactive oxygen species (increased generation). AR: androgen receptor.