Table 4.

Changes of IL-1β, IL-18, NLRP3 and CASP1 concentration in TMJOA groups with twice HA injections

	First injection	Second injection	P
IL-1β (pg/ml)	656.50 ± 272.06	267.15 ± 159.61	< 0.001
IL-18 (pg/ml)	397.73 ± 60.03	132.06 ± 101.24	< 0.001
NLRP3 (ng/ml)	0.61 ± 0.11	0.42 ± 0.02	< 0.001
CASP1(pmol/L)	165.34 ± 29.48	169.47 ± 37.72	0.549