MEWF	methanol extract of W. fruticosa leaves
NHFMEWF	n-hexane fraction of methanol extract of W. fruticosa leaves
EAFMEWF	ethyl acetate fraction of methanol extract of W. fruticosa leaves
ADME/Tox	absorption, distribution, metabolism, excretion, and toxicity
DM2	type 2 diabetes mellitus
PPHG	postprandial hyperglycemia
HPA	human pancreatic α-amylase
ROS	reactive oxygen species
OS	oxidative stress
NADPH	nicotinamide adenine dinucleotide phosphate
MDD	major depressive disorder; 5-HT, 5-hydroxytryptamine
NO	nitric oxide
NOS	nitric oxide synthase
DNA	deoxyribonucleic acid; RT, room temperature
OD	optical density; Rpm, rotation per minute; p.o., orally; b.w., bodyweight
SERT3	serotonin transporter 3
DAT	dopamine transporter
MAO-A	monoamine oxidase A
nNOS	neuronal nitric oxide synthase
OPLS	optimized potentials for liquid simulations
RO5	rule of Five
ANOVA	analysis of variance
SPSS	statistical package for social science
GABA	gamma-aminobutyric acid; i.p., intraperitoneal
GI	gastrointestinal
P-gp	p-glycoprotein
CYP	cytochrome P450 enzymes