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. 2021 Feb 3;10(2):287. doi: 10.3390/plants10020287

Table 7.

Toxicological profiles of the selected compounds from W. fruticosa leaves.

Compound(s) Toxicological Parameters
Ames Toxicity Hepatoxicity Skin Sensitization Rat Oral Acute Toxicity
LD50 (mg/kg) Toxicity Classification
GA No No No 1606 Class 4 in AD
MTMG Yes No No 2815 Class 5 in AD
EA No No No 1712 Class 4 in AD
Q3LA No No No 2745 Class 5 in AD
M3LA No No No 2748 Class 5 in AD
Q3DG No No No 3501 Class 5 in AD

In AD, compounds fall within the applicability domain of models; GA, gallic acid; MTMG, methyl tri-O-methylgallate; EA, ellagic acid; Q3LA, quercetin 3-O-α-L-arabinopyranoside; M3LA, myricetin 3-O-α-L-arabinopyranoside; Q3DG, quercetin 3-O-(6″-galloyl)-β-D-galactopyranoside.