Table 4.
Top 10 enriched pathways and a gene ontology of 426 genes associated with skin diseases with alterations in the Notch signaling pathway.
| Reactome ID | Pathway Description | GO ID | GO Description |
|---|---|---|---|
| R-HSA-449147 | Signaling by Interleukins | GO:0034097 | Response to cytokine |
| R-HSA-6785807 | Interleukin-4 and Interleukin-13 signaling | GO:0019221 | Cytokine-mediated signaling pathway |
| R-HSA-6783783 | Interleukin-10 signaling | GO:0071345 | Cellular response to cytokine stimulus |
| R-HSA-877300 | Interferon gamma signaling | GO:0002376 | Immune system process |
| R-HSA-447115 | Interleukin-12 family signaling | GO:0006952 | Defense response |
| R-HSA-8854691 | Interleukin-20 family signaling | GO:0009605 | Response to external stimulus |
| R-HSA-913531 | Interferon Signaling | GO:0044419 | Interspecies interaction between organisms |
| R-HSA-380108 | Chemokine receptors bind chemokines | GO:0070887 | Cellular response to chemical stimulus |
| R-HSA-451927 | Interleukin-2 family signaling | GO:0010033 | Response to organic substance |
| R-HSA-1059683 | Interleukin-6 signaling | GO:0051707 | Response to other organisms |