Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Functions of PINK1 in healthy and damaged mitochondria. In healthy mitochondria, PINK1 regulates apoptosis, mitochondrial respiration, cell growth or differentiation, and autophagy/mitophagy. In damaged mitochondrial, PINK1 plays a key role in autophagy/mitophagy, mitochondrial fission and fusion, mitochondrial biogenesis, mitochondrial motility, and mitochondria-derived vesicles (MDVs) as well as calcium signalling and apoptosis.
