3′UTR |
3′untranslated region |
39 UTRs |
39 untranslated regions |
AGEs |
advanced glycation end products |
AKT |
serine/threonine protein kinase B |
AIM |
absentin-melanoma |
ALRs |
absentin-melanoma-like receptors |
AMPK |
adenosine monophosphate-activated protein kinase |
ASC |
apoptosis-associated speck-like protein |
CARD |
C-terminal caspase recruitment domain |
CRP |
C-reactice protein |
CTLs |
C-type lectins |
DAG |
diacylglycerol |
DAMPs |
damage-associated molecular patterns |
dsDNA |
bacterial double-stranded DNA |
ET-1 |
endothelin-1 |
ER |
endoplasmic reticulum |
ERK1/2 |
extracellular signal-regulated kinases 1/2 |
eNOS |
endothelial NO synthase |
FFAs |
saturated free fatty acids |
G3PDH |
glyceraldehyde-3-phosphate dehydrogenase |
GSH |
glutathione |
GSK3β |
glycogen synthase kinase 3 beta |
GLUT1 |
glucose transporter 1 |
GLUT4 |
glucose transporter 4 |
HFD |
high-fat diet |
IAAP |
islet amyloid polipeptyde |
ICAM-1 |
intercellular adhesion molecule 1 |
ICE |
interleukin-1β-converting enzyme |
IDF |
International Diabetes Federation |
IL |
interleukins |
IRAK1 |
IL-1 receptor-associated kinase |
IRS-1 |
insulin receptor substrate-1 |
JNKs |
c-Jun N-terminal kinases |
LRR |
leucine-rich repeats |
MAPK |
mitogen-activated protein kinases |
MCP1 |
monocyte chemoattractant protein 1 |
MCT1 |
monocarboxylate transporter 1 |
miRNAs |
microRNAs |
mRNAs |
messenger RNAs |
mTOR |
mechanistic target of rapamycin |
mTORC |
mechanistic target of rapamycin complex |
NBD |
nucleotide-binding domain |
NF-κB |
nuclear factor kappa-light-chain-enhancer of activated B cells |
NLRP |
nucleotide-binding oligomerization domain-like receptor with a pyrin domain |
NLRP3 |
protein 3 inflammasome complex |
NLR |
Nod-like receptor |
NO |
nitric oxide |
NOD |
nucleotide-binding oligomerization domain |
NOD |
nucleotide oligomerization domain |
NPAS3 |
neuronal Per-Arnt-Sim domain protein 3 |
NT |
nucleotides |
ORP8 |
oxysterol-binding-protein-related protein 8 |
PAMPs |
pathogen-associated molecular patterns |
PARP-1 |
poly (ADP ribose) polymerase 1 |
PERK |
protein kinase-like endoplasmic reticulum kinase |
PI3K |
phosphatidylinositol 3-kinase |
PKC |
protein kinase C |
PKCα |
protein kinase C alpha |
PRRs |
pattern recognition receptor |
PYD |
pyrin domain |
RIG-I |
retinoic acid inducible gene-I |
RLRs |
RIG-I-like receptors |
ROS |
reactive oxygen species |
SFAs |
saturated fatty acids |
SGK1 |
serum- and glucocorticoid-inducible kinase 1 |
T2DM |
type 2 diabetes mellitus |
TGF-β |
transforming growth factor beta |
Th |
T helper |
TLRs |
toll-like receptors |
TNFα |
tumor necrosis factor alpha |
TNFR |
tumor necrosis factor receptor |
TORC1 |
target of rapamycin complex 1 |
TRAF6 |
TNFR-associated factor 6 |
TXN |
thioredoxin |
TXNIP |
thioredoxin-interacting protein |
UPR |
unfolded protein response |
VCAM-1 |
vascular cell adhesion molecule |
VEGF |
vascular endothelial growth factor |