Table 1.
0.3ES | 0.5ES | 0.7ES | 1.0ES | |
---|---|---|---|---|
0.3LD | 16.3 (11, 7, 25) | 13.89 (8, 10, 25) | 11.85 (6, 8, 29) | 9.95 (6, 8, 29) |
0.5LD | 19.3 (17, 9, 17) | 17.99 (12, 11, 20) | 15.87 (8, 14, 21) | 12.71 (4, 14, 25) |
0.7LD | 20.17 (17, 14, 12) | 19.88 (17, 19, 7) | 18.72 (9, 22, 12) | 16.05 (4, 17, 22) |
1.0LD | 19.95 (15, 15, 13) | 20.31 (17, 18, 8) | 20.1 (16, 21, 6) | 19.19 |
Values outside the parentheses are the average adjusted log AUC values, while those within the parentheses refer to those targets that improved by 1 adjusted log AUC value, stayed within ±1 log AUC, and diminished by 1 adjusted log AUC value vs the standard scoring function (1.0ES+1.0vdW+1.0LD) (see Table S1 for full results).