Table 2.
The composition of each sample for A549 cells treated by 8-hydroxyoctanoic acid (8-HOA), Prostaglandin E2 (PGE2), dihomo-γ-linolenic acid (DGLA), delta-5-desaturase inhibitor (D5Di), and DGLA + D5Di.
| Sample | Cell | DGLA | D5Di | 8-HOA | PGE2 | Estimated 8-HOA/PGE2 Level |
|---|---|---|---|---|---|---|
| 1 | 106 A549 | none | none | none | none | Low 8-HOA; low PGE2 |
| 2 | 106 A549 | none | none | 0.6 μg/mL | none | High 8-HOA; low PGE2 |
| 3 | 106 A549 | none | none | none | 6 μg/mL | Low 8-HOA; high PGE2 |
| 4 | 106 A549 | 100 μM | none | none | none | Low 8-HOA; high PGE2 |
| 5 | 106 A549 | none | 10 μM | none | none | Low 8-HOA; low PGE2 |
| 6 | 106 A549 | 100 μM | 10 μM | none | none | High 8-HOA; low PGE2 |