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Hot-melt extrusion (HME) processing conditions to study the effect of HME processing temperature on lipid-based formulations and drug release profiles.
| HME Parameters | Processing Conditions |
|---|---|
| Barrel Temperature Profiles (°C) | Zone 2–7: 77 °C, Zone 8–10 and Die: 70 °C |
| Zone 2–7: 75 °C, Zone 8–10 and Die: 70 °C | |
| All zones: 70 °C | |
| Screw Speed (rpm) | 50 rpm |
