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. 2021 Feb 4;11(2):216. doi: 10.3390/biom11020216

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Cichoriin dockings conformations against COVID-19 targets. Cichoriin (magenta) was docked to the main pharmaceutically attractive targets (rainbow ribbon 3D protein structure) of SARS-CoV-2 with the COVID-19 docking server. As depicted in this figure, cichoriin achieves the most stable conformations with against the main protease (papain-like protease), Nsp3 (AMP site), Nsp3 (MES site), RdRp (RTP site), RdRp (RNA site), Helicase (ADP site), Helicase (NCB site), Nsp14 (ExoN), Nsp14 (N7-MTase) and N protein (NCB site).