Table 2.
Examples of chemical-responsive nanomaterials and their biomedical applications.
| Nr. Crt. | Stimuli | Nanomaterial | Application | Reference. |
|---|---|---|---|---|
| 1. | pH |
Ppoly (ethylene glycol)-Ag nanoparticle PEG-Ag NPs |
Antibacterial, wound healing | [77] |
| 2. | pH |
Hybrid ultra-pH-sensitive (HyUPS) nanotransistor HyUPS nanotransistors |
Receptor-mediated endocytosis in tumor cells | [78] |
| 3. | pH |
Layered double hydroxides-zinc (II) phthalocyanine containing octasulfonate nanohybrid LDH-ZnPcS8 nanohybrid |
Theranostics | [79] |
| 4. | pH | Melanin-like nanoparticles | Photoacoustic imaging of tumors | [80] |
| 5. | pH |
polylactic acid-Resveratrol PLA-RSV |
Drug delivery | [81] |
| 6. | pH |
Poly(carboxybetaine methacrylate)-nanodiamonds PCBSA-@-NDs |
Theranostics | [82] |
| 7. | Redox |
Poly (ethylene glycol)-Pluronic F68-nanoscale covalent organic frameworks F68@SS-COFs |
Cancer therapy | [83] |
| 8. | Redox |
Hyaluronic acid–chitosan–lipoic acid nanoparticles (HACSLA-NPs) |
Breast cancer therapy | [84] |
| 9. | Redox |
Folate redox-responsive chitosan nanoparticles FTC-NPs |
Anticancer drug delivery | [85] |
| 10. | Redox |
Poly (ethylene glycol) conjugated to paclitaxel via disulfide linkage PEG2000-S-S-PTX |
Prodrug for breast cancer cells | [86] |
| 11. | Redox | Prodrug/AgNPs hybrid nanoparticles | Drug delivery | [87] |
| 12. | Redox |
P[(2-((2- ((camptothecin)-oxy)ethyl)disulfanyl)ethylmethacrylate) -co- (2-(D-galactose)methylmethacryl-ate)] and silver nanoparticles P(MACPTS-co-MAGP)@AgNPs nanoparticles |
Drug release | [88] |