Table 1.

Predicted integrin α₄β₁/β₇ amino acids with contact with the EDA-FN peptide.

Mode	Score	Subunit	Integrin Amino Acid in Contact (≤3 Å)
1	−5.0	α4	E121, D123, *N124, *K149, I154, K155, *N156, E157, *N158, *K159, F191, G192
		β1	V192, M193, I196, S197, T198, T199, P200, *A201, *K202, L203, P206, C207, T208, S209, N244, L245, *G291, H312
		β7	V201, P203, V205, S206, T207, V208, P209, S210, *K211, L212, P215, C216, P217, T218, *N254, L255, *G301
2	−4.4	α4	E121, D123, *N124, R147, *K149, I154, K155, *N156, *K159, Y220
		β1	Y153, V192, M193, T199, P200, A201, *K202, L203, P206, C207, T208, G243, *N244
		β7	V201, P203, P209, S210, *K211, L212, P215, C216, P217, T218, *N254, L255
3	−3.3	α4	I154, K155, *N156, E157, N158, K159, K190, F191, G192
		β1	Y153, T199, P200, *A201, *K202, *R204, *N205, P206, C207, T208, L245
		β7	V201, P203, P209, S210, *K211, L212, *R213, P215, C216, T218, L255
4	−3.1	α4	I154, N156, E157, K159, K190, F191, Y220, W221
		β1	S197, T198, P200, A201, *K202, *R204, P206, C207, T208, S209, *N244, L245
		β7	V201, P203, P209, S210, *K211, L212, *R213, P215, C216, P217, T218, G253, *N254, L255
5	−2.6	α4	E121, D123, N124, I154, K155, *N156, E157, N158, K159, K190, F191, G192, Y220, W221
		β1	Y153, *S197, T199, P200, *A201, *K202, R204, N205, P206, C207, T208, G243, N244
		β7	P209, S210, *K211, L212, *R213, P215, C216, T218, G253, N254
6	−2.2	α4	E121, *N124, R147, I154, K155, *N156, *E157, *N158, *K159
		β1	T191, V192, T198, *T199, P200, A201, K202, L203, T208, G291, G292, H312
		β7	T200, V201, L202, *T207, V208, P209, S210, K211, L212, T218, G301
7	+3.3	α4	I154, K155, *N156, N158, *K159, F191
		β1	*T191, V192, *S197, *T198, T199, P200, *A201, K202, L203
		β7	*T200, V201, *S206, *T207, V208, P209, S210, *K211, L212

* indicates predicted H-bond donor.