Figure 3.

Predicted heatmaps of test cases showing distribution of machine-recognized features. First column: heatmaps showing the distribution of pathomorphological features predicted from scanned H&E whole-slide images; second and third columns: heatmaps of the same cases showing the distribution of CD276 immunoreactivity before and after image registration, respectively; last column: CD276 expression mapped to pathomorphological features following image registration. Note: Probability heatmaps in the second column were generated using prediction probabilities as weighting factors for pseudo-color mapping, which were then converted into classification heatmaps before image registration (third column) and image fusion (fourth column).