Table 1.
Age | 71.34 ± 15.9 |
Female sex (vs male) | 40 (46%) |
BMI (kg/m2) | 27.49 ± 4.43 |
Time from symptom onset to hospital admission (days) | 6.78 ± 4.35 |
Time from symptom onset to ultrasound performance (days) | 24.65 ± 13.01 |
Time from admission to ultrasound performance (days) | 19.28 ± 11.39 |
Charlson index | 4.43 ± 3.01 |
Smoking (pack years) | |
<5 | 61 (70.1%) |
≥5 | 26 (29.9%) |
Comorbidities | |
Hypertension | 53 (60.9%) |
Diabetes | 29 (33.3%) |
Dementia | 27 (31%) |
Structural cardiac disease | 24 (27.6%) |
Chronic obstructive lung disease/asthma | 20 (23%) |
Stroke | 10 (11.5%) |
Chronic kidney disease (eGFR < 30 ml/min) | 7 (8%) |
Coronary heart disease | 6 (6.9%) |
Previous antiplatelet therapy | 22 (25.3%) |
Previous anticoagulant therapy | 15 (17.2%) |
Predisposing factors for VT | |
History of VTE (either DVT, PE, or both) | 2 (2.3%) |
Immobilization | 69 (79.3%) |
Central vein catheterisation | 24 (27.6%) |
Other common risks factors for VT | 13 (14.9%) |
ICU admission | 26 (29.9%) |
Length of stay in ICU (days) | 24.93 ± 13.08 |
Mechanical invasive ventilation | 23 (26.4%) |
Clinical severity score | |
Mild | 7 (8%) |
Moderate | 26 (29.9%) |
Severe | 27 (31%) |
Critical | 27 (31%) |
Treatment with anti-inflammatory drugs (during hospitalization) | |
None | 37 (42.5%) |
Steroids | 48 (55.2%) |
Tocilizumab | 22 (25.3%) |
Anakinra | 3 (3.4%) |
D-dimer (peak), mg/L (IQR) | 10.02 ± 12.2 (1.4–12.9) |
D-dimer at time of CTPA performance (mg/L) | 8.01 ± 10.72 |
BMI = body mass index; eGFR = estimated glomerular filtration rate; NOAC = novel oral anticoagulants; VT = venous thrombosis; VTE = venous thromboembolism; PE = pulmonary embolism; DVT = deep venous thrombosis; ICU = intensive care unit; LMWH = low-molecular-weight heparin; IQR = interquartile range; CTPA = computed tomography pulmonary angiogram.
Quantitative variables are expressed in mean ± standard deviation, except those related to time, which are expressed in median.