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. 2021 Feb 20;2021:6633825. doi: 10.1155/2021/6633825

Figure 1.

Figure 1

The systolic blood pressure (SBP), body weight, and serum levels of cytokines in Wistar-Kyoto rats (WKY) and spontaneous hypertensive rats (SHR). (a) SBP was measured using the tail-cuff method. SBP of SHR significantly higher at adult (15 weeks) compared with juvenile (5 weeks). (b) The body weights of the WKY and SHR revealed comparable in 5 weeks and 15 weeks. The serum levels of (c) a proinflammatory cytokine (IL-17A) and (d) an anti-inflammatory cytokine (IL-10) were measured using ELISA in juvenile and adult rats. The serum levels of IL-17A were higher in SHR than in WKY, whereas the levels of IL-10 were lower in SHR than in WKY. Data are the mean ± SEM of 6 independent experiments. Most SEMs were too small to be seen out of symbols (∗P < 0.05, ∗∗P < 0.01 vs. WKY; ##P < 0.01 vs. corresponding juvenile rats by two-way ANOVA followed by the post hoc Duncan test).