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. 2021 Feb 20;2021:6633825. doi: 10.1155/2021/6633825

Figure 4.

Figure 4

T cell profiles of PBMCs in juvenile recipient WKY and SHR for 4 days after transferring Th17 cells from adult donor SHR. Representative flow cytometric analysis revealed the proportion of (a) CD4+IL-17A+ (Th17) cells and (b) CD4+FoxP3+ (Treg) cells of PBMCs in juvenile recipient WKY or SHR. (c) Quantification revealed that CD4+IL-17A+ (Th17) cells after the transfer of Th17 cells significantly increased compared with the vehicle in juvenile recipient WKY and SHR. (d) Quantification revealed that the proportion of CD4+FoxP3+ (Treg) cells after transfer of Th17 cells significantly increased compared with the vehicle in juvenile recipient SHR. Data are the mean ± SEM of 6 independent experiments (∗P < 0.05, ∗∗P < 0.01 vs. vehicle group by two-way ANOVA followed by the post hoc Duncan test).