Table 7.

PASS prediction coefficient with non-tumor cell lines based on the best phytocompound derivatives with lowest IC50 obtained after QSAR analysis

Compounds	Pa*	Pi**	Cell line	Cell line name	Tissue/organ
Withaferin-A mol 61	0.254	0.071	WI-38 VA13	Embryonic lung fibroblast	Lung
	0.163	0.041	HUVEC	Umbilical vein endothelial cell	Endothelium
	0.092	0.032	MT2	Lymphocyte(HTLV-producing cell line)	Blood
Withaferin-A mol 64	0.226	0.088	WI-38 VA13	Embryonic lung fibroblast	Lung
	0.208	0.097	HEK293	Embryonic kidney fibroblast	Kidney
	0.143	0.050	HUVEC	Umbilical vein endothelial cell	Endothelium
	0.085	0.043	MT2	Lymphocyte (HTLV-1 producing cell line)	Blood
	0.135	0.117	NHDF	Fibroblast	Skin