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Increased Familial Risk of Erosive Hand Osteoarthritis.
| Relationship | Cases | Controls | Relative Risk (Coefficient and 95% CI) | p-value | ||
|---|---|---|---|---|---|---|
| Affected | Unaffected | Affected | Unaffected | |||
| First-degree relative | 8 | 2654 | 15 | 27902 | 5.53 (2.1 – 14.58) | 0.001 |
| Second-degree relative | 2 | 5661 | 10 | 57601 | 2.14 (0.46 – 10.06) | 0.334 |
| First cousins | 6 | 6835 | 34 | 73694 | 11.08 (1.09 – 112.58) | 0.166 |
| Second cousins | 18 | 49275 | 289 | 520441 | 0.66 (0.4 – 1.06) | 0.087 |
Abbreviations: CI - 95% confidence interval
