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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Methods. 2020 Oct 9;187:28–43. doi: 10.1016/j.ymeth.2020.10.002

Figure 3. Key principle comparison of MRE-seq, MeDIP-seq and MBD-seq.

Figure 3

5mC, 5-methylcytosin; “M” in the yellow hexagon indicates DNA methylation; MBD, methyl-CpG-binding domain protein; MeDIP, methylated DNA immunoprecipitation; MRE, methylation sensitive restriction enzyme; -seq, sequencing.