Figure 5. DMOG intervention improved renal hypoxia but did not change endothelial cell number and function.
Pimonizadole adducts immunostaining in tubular epithelial cells was less when DMOG was added after folic acid injury (×100) (A). Expression of VEGF-A mRNA in kidney cortex increased in response to DMOG after folic acid injury (B). CD31 mRNA was not different in response to DMOG after folic acid injury (C). Extravasated Evans blue dye did not change in the DMOG vs. vehicle treatment group (D).